Housefull is a romantic comedy film that revolves around the life of Prem (Akshay Kumar), a young man who falls in love with a girl named Manjari (Deepika Padukone). However, their relationship is put to test when Prem's best friend, Sameer (Randeep Hooda), also falls in love with Manjari. The movie takes a turn when Prem and Sameer decide to marry two women, Aarti (Lara Dutta) and Pooja (Bipasha Basu), respectively, to help their friend.